Lowry M, Wang Y, Dagan T, Mitchell A. Colibactin leads to a bacteria-specific mutation pattern and self-inflicted DNA damage. Genome Research 2024 (Genome Research, PubMed)

X thread - article breakdown on X

Lowry M, Mitchell A. Colibactin-induced damage in bacteria is cell contact independent. mBio 2024 (mBio, bioXiv, PubMed)

Noto Guillen M, Li C, Rosener B, Mitchell A. Antibacterial activity of nonantibiotics is orthogonal to standard antibiotics. Science 2024 (Science, PubMed)
Thread on X - article breakdown on X (formerly twitter)
Covered on Nature Reviews Drug discovery, Chemistry World.

Mitchell A. Tumor-microbiome-drug interactions approached at a systems level (in review)

Sayin S. and Mitchell A. Functional Assay for Measuring Bacterial Degradation of Gemcitabine Chemotherapy. Bio-Protocol 2023 (Bio-Protocol, PubMed)

Sayin S., Rosener B, Li C., Ho B., Ponomarova O, Ward D, Walhout AJ., Mitchell A. Evolved bacterial resistance to the chemotherapy gemcitabine modulates its efficacy. eLife 2023 (eLife, PubMed)
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Noto Guillen M, Rosener B, Sayin S, Mitchell A. Assembling stable syntrophic Escherichia coli communities by comprehensively identifying beneficiaries of secreted goods. Cell Systems Biology 2021 (Cell Systems, PubMed)
#Tweetorial - article breakdown on twitter

Khoshkenar P*, Lowry E*, Mitchell A. Rapid signaling reactivation after targeted BRAF inhibition predicts the proliferation of individual melanoma cells from an isogenic population. Scientific reports 2021 (Scientific Reports / PubMed)
* equal contribution
#Tweetorial - article breakdown on twitter

Rosener B, Sayin S, Oluoch PO, García González AP, Mori H, Walhout AJ, Mitchell A. Evolved bacterial resistance against fluoropyrimidines can lower chemotherapy impact in the Caenorhabditis elegans host. eLife 2020 (eLife / PubMed)

Xavier JB, et al. The Cancer Microbiome: Distinguishing Direct and Indirect Effects Requires a Systemic View. Trends in Cancer 2019 (Trends in Cancer)

Dahan O, Dorfman BS, Sayin S, Rosener B, Hua T, Yarden A, Mitchell A. Harnessing robotic automation and web-based technologies to modernize scientific outreach. PLoS Biology 2019 (PLoS Bio / PubMed)

Shraga A., Olshvang I., Zabolinsky A., Khoshkenar P., Germain N., Shurrush K., Carvalho K., Avram L., Albeck S., Unger T., Lefker B., Subramanyam B., Hudkins RR. L., Mitchell A., Shulman Z., Kinoshita T., London N. Covalent docking identifies a potent and selective MKK7 inhibitor
Cell Chemical Biology 2018 (Cell Chem Bio / PubMed)

Bugaj, LJ., Sabnis, A., Mitchell A., Garbarino J., Bivona T., Toettcher, JE., and Lim W.  Cancer mutations and targeted drugs can disrupt dynamic signal encoding by the Ras-Erk pathway.
Science 2018 (Science / PubMed)

Mitchell A. Lim WA. Cellular perception and misperception: Internal models for decision-making shaped by evolutionary experience.
BioEssays 2016 (BioEssays / PubMed)

Mitchell A., Wei P., and Lim WA. Oscillatory stress stimulation uncovers an Achilles heel of the yeast MAPK signaling network. 
Science 2015 (Science / PubMed)

• Featured in Developmental Cell: Cybernetics, Redux: An Outside-In Strategy for Unraveling Cellular Function

• Featured in Phys.org: Sensory illusion causes cells to self-destruct

Yona AH, Manor YS, Herbst RH, Romano GH, Mitchell A, Kupiec M, Pilpel Y, Dahan O. Chromosomal duplication is a transient evolutionary solution to stress. 
PNAS 2012 (PNAS / PubMed)

Mitchell A, and Pilpel Y, A Mathematical Model for Adaptive Prediction of Environmental Changes by Microorganisms. 
PNAS 2011 (PNAS / PubMed)

Mitchell A, Romano GH, Groisman B, Yona A, Dekel E, Kupiec M, Dahan O, Pilpel Y. Adaptive Prediction of Environmental Changes by Microorganisms.
Nature 2009 (Nature / PubMed)

• Featured in Nature News and Views: Microbes exploit groundhog day

• Featured in National Geographic Blog: How E. coli sees the Futur

Mayrose I*, Mitchell A.*, and Pupko T. (*equal contribution). Site-Specific Evolutionary Rate Inference: Taking Phylogenetic Uncertainty into Account. 
Journal of Mol Evolution 2005 (PubMed)

Mitchell A, and Graur D. The Pattern of Spontaneous mutation In Mycobacterium leprae and a comparison of mutation patterns across large evolutionary distances. 
Journal of Mol Evolution 2005 (PubMed)